Leuprolide

Product Name Leuprolide

Sequence? pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt

Cas No. 53714-56-0

Purity (HPLC) Not less than 98%

Molecular Formula C59H84N16O12

Molecular Weight 1209.4

Appearance White or slightly yellowish white powder

Water ≤7.0%

Acetic acid ≤10.0%

IR spectrum in accordance

Applications:

Mainly has a strong angiotensin II vasoconstriction and increase in blood pressure. The mechanism is: 1. So that the body arteriole smooth muscle contraction, increased peripheral resistance; 2. So increase the release of adrenal aldosterone, causing sodium retention, increased blood volume; 3. Directly contribute to renal tubular sodium and water reabsorption; 4. So the brain central nervous sympathetic vasoconstrictor activity, causing increased peripheral vascular resistance; 5. Stimulate the adrenal medulla to release epinephrine and norepinephrine