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Ketamine, sold under the brand name Ketalar among others, is a medication

Common side effects include psychological reactions as the medication wears off.^[22] These reactions may include agitation, confusion, or hallucinations

Ketamine was discovered in 1962, first tested in humans in 1964, and was approved for use in the United States in 1970.^[21][25] Shortly after its US approval it was extensively used for surgical anesthesia in the Vietnam War