Globally Popular Dimethocain CAS 94-15-5 with The Latest Date of Production, 100% Pass Custom Anesthetic

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Larocaine Anesthesia Injection CAS 94-15-5 safe delivery free sample


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(DMC, larocaine), a synthetic derivative of co-caine, is a widely distributed \"legal high\" consumed as a \"new psychoactive substance\" (NPS), originally was used in the 1930s as an anesthetic, primarily in dentistry, ophthalmology, and otolaryngology. This drug completely inhibits dopamine transporter and has had the potential for abuse. Dimetho-caine is intended for forensic and research purposes.

Sample USE GUIDE

In Vivo Use Guide
in rhesus monkeys: When responding was stable, dimetho-caine (0.030-1.7 mg/kg/ infusion) was substituted for the cocaine training dose. Dimetho-caine administration produced higher response rates compared with that of procaine, and was a more potent reinforcer. Drug effects on behavior were related to DAT occupancy in monkey striatum during neuroimaging with positron emission tomography (PET). DAT occupancy was determined by displacement of 8-(2-[(18)F]fluroethyl)2beta-carbomethoxy-3beta-(4-chlorophenyl)nortropane (FECNT). DAT occupancy was between 66 and 82% and <10-41% for doses of dimetho-caine and procaine that maintained maximum response rates, respectively. Acute administration of dimetho-caine (10-40 mg/kg, IP) significantly increased locomotor activity and time spent on the drug-paired side and reduced the relative number of entries and time spent on the open arms of the plus-maze in mice.
Route of Administration: Intraperitoneal
In Vitro Use Guide
Dimetho-caine showed full displacement of [3H]2-beta-carbomethoxy-3-beta-(4-fluorophenyl)tropane 1.5-naphthalenedisulfonate (CFT) binding (0-30 microM tested) and full inhibition of dopamine uptake (0-100 microM tested). Dimetho-caine was only slightly less potent than cocaine with an estimated Ki of 1.4 micorM and an IC50 value of 1.2 microM for [3H]CFT binding and dopamine uptake.


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Items Standard Results of analysis
Appearance White to class white powder Class white powder
Solubility Almost insoluble in water,

soluble in dimethyl sulfoxide,

slightly soluble in dichloromethane

Conforms
Speicific rotation +78.0°~+84.0° +82.3°
Ordinary impurities

(Do not calculate isomer A+C)

Single impurity≤0.15% 0.03%
Total impurities≤1.0% 0.09%
Calculate isomer A≤0.15% 0.02%
B≤0.1% Not detected
C≤0.1% Not detected
Loss on drying ≤0.5% 0.31%
Residue on ignition ≤0.1% Conforms
Heavy metal 20ppm Conforms
Assay 97.5%-102.0% 99.8%
Conclusion :The test results conform with USP36.

Product Name Dimethocaine
CAS 94//15//5
Density 1.0±0.1 g/cm3
Boiling Point 403.5±25.0 °C at 760 mmHg
Molecular Formula C16H26N2O2
Molecular Weight 278.390
Flash Point 197.8±23.2 °C
Exact Mass 278.199432
PSA 55.56000
LogP 3.55
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.529



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Product Name Benzocaine
CAS 94-09-7
Density 1.1±0.1 g/cm3
Boiling Point 310.7±15.0 °C at 760 mmHg
Melting Point 88-90 °C
Molecular Formula C9H11NO2
Molecular Weight 165.189
Flash Point 164.2±17.9 °C
Exact Mass 165.078979
PSA 52.32000
LogP 1.95
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.555
Storage condition 0-6°C
Stability Stable. Combustible. Incompatible with strong oxidizing agents.



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Product Name Tetracaine hydrochloride
CAS 136-47-0
Boiling Point 389.4ºC at 760 mmHg
Melting Point 149°C
Molecular Formula C15H25ClN2O2
Molecular Weight 300.824
Flash Point 189.3ºC
Exact Mass 300.160461
PSA 41.57000
LogP 3.49200
Vapour Pressure 2.87E-06mmHg at 25°C
Storage condition Refrigerator

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Anhui Moker New Material Technology Co. Ltd is a high-tech enterprise engaged in the area of chemical products. It includes a combination of pharmaceutical intermediates, plant extracts, chemical reagent, animal pharmaceutical, agrochemical intermediates, antibiotic etc. Based on the advantage of both trader and manufacturer, we have been strictly managing the whole trade process providing customers with all-round service such as R&D, quality control, logistics and so on. We firmly believe that quality is the life of our company and customer\'s success is our success. Reliable quality and excellent service are our permanent commitment. We wish to establish a long-term mutual beneficial relationship with more friends in the future and give our customers best products and service that they expect and deserve.


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